In the United States and Europe, Clomid (clomiphene citrate) is a commonly prescribed fertility drug. This medication is often ordered as to help stimulate the ovaries and to assess for ovulation. Clomid forces the body to produce more hormones and egg follicles than usual, so the woman will develop more than one mature egg. Because of extra eggs, the chances of getting pregnant with twins is increased.
Clomid Success Rates
Clomiphene citrate has been used for fertility treatment for over 50 years. The goal of treatment is to induce ovulation and normalize menstrual cycles. Of women prescribed Clomid, 80% successfully ovulate, but only 50% of these women will go on to get pregnant.
One thing that limits the success of Clomid is side effects, such as cervical mucus changes and endometrial effects. In addition, another factor that affects success rates of Clomid is that many women have secondary infertility factors. In a recent study, researchers found that 87% of women who ovulate on Clomid have an additional cause of infertility, such as tubal disease, pelvic lesions, and endometriosis.
For women who get pregnant naturally, the chance of having twins is around 2%. However, taking Clomid increases a woman’s chances of delivering twins, but not drastically. According to statistics, Clomid causes twin pregnancies around 10% of the time, and less than 1% of women taking Clomid have triplets or quadruplets.
According to one clinical trial, 0.5% of women on Clomid had triplets, and 0.3% had quadruplets. Of women who conceive twins, most children are not identical. According to clinical studies, only 1 of 5 twin pregnancies resulting from Clomid therapy are identical twins. This means 80% of twin pregnancies result in fraternal twins.
Factors that Increases Twin Rates on Clomid
Certain factors increase the likelihood of a woman delivering twins while taking Clomid. These include:
- Age – Women younger than 25 years of age are more likely to have twins while on Clomid.
- Ovulation – Only women who have trouble ovulating should take Clomid. Anyone who ovulates regular, and takes this drug, has an increased chance of having twins.
- Dose – Taking more than the recommended dose of Clomid increases chances of delivering twins.
How Clomid Works
Clomiphene citrate works by blocking the effects of estrogen in your body. By blocking estrogen action, this effect tricks your body to produce FSH and LH, which are hormones necessary for ovulation. FSH causes the eggs to mature in the ovaries, and LH triggers the eggs release from the follicles. You take Clomid in pill form for five days of your menstrual cycle, and as long as six months.
Most women are advised to start Clomid within five days of the period. Progesterone is also given to keep your reproductive cycle regular and to re-establish periods if you have irregular menses. Ovulation is expected between 5-9 days after you have taken the last Clomid pill. It is possible that you ovulate and conceive in the first month, or it may take several months before you ovulate regularly. For some women, treatment is continued for a full year. Unfortunately, not all women respond to Clomid.
Clomiphene citrate, like all medications, has some side effects. Make sure to talk to your local Los Angeles fertility doctors if you have any concerns. These include:
- Mood swings
- Hot flashes
- Blurred vision
- Weight gain
- Heavy periods
- Breast tenderness
With clinics throughout Southern California, call Pacific Reproductive Center today!