What Happens After IUI: Day by Day


When you and your partner decide to try IUI (intrauterine insemination) after a frustrating experience with infertility, it can leave you feeling excited, hopeful, and curious about what to expect in the days that follow.

Here is an IUI timeline to help you understand the typical day-by-day experience of IUI, how long it takes, when implantation typically occurs, and what symptoms to watch for 2-14 days post-IUI.

How Long Does IUI Take?

IUI is a fertility procedure that typically takes 5-10 minutes. Before the procedure, your doctor will need to collect and prepare a sperm sample from your partner or a donor.

The procedure itself is like a Pap smear and involves inserting a small, thin, flexible tube filled with sperm concentrate into the uterus through the cervix.

IUI is an outpatient procedure at Pacific Resource Center and is performed right in our fertility clinic.

How Long After IUI Is Implantation?

Implantation after IUI usually occurs 6-12 days after ovulation and a well-timed procedure.

Typical IUI Timeline

Here are general timelines for IUI with and without Clomid, a fertility medication used to help induce ovulation, so you know what to expect.

Natural Cycle IUI Timeline

  • Cycle day 11
    Begin testing for a surge in the luteinizing hormone (LH), which indicates ovulation.
  • Cycle day 12
    Conduct an ultrasound to confirm the preovulatory follicle and evaluate the uterine lining.
  • After ultrasound
    Take a “trigger shot” to prompt ovulation. This is an injectable fertility medication that contains hCG (human chorionic gonadotropin) and is used to trigger ovulation.
  • After ovulation
    Your doctor will manage the collection, preparation, and insemination of sperm from your partner or a donor.

Clomid Cycle IUI Timeline

  • Cycle day 3
    Take Clomid for 5-7 days.
  • Midcycle
    Conduct bloodwork to test estradiol and progesterone levels and an ultrasound to measure uterine lining thickness and follicles.
  • When follicles reach 18 mm
    Take a “trigger shot” to prompt ovulation.
  • Days 1-2 following ovulation
    Your doctor will manage the collection, preparation, and insemination of sperm from your partner or a donor.

IUI Success Symptoms Day by Day

Some women experience post-IUI symptoms that may indicate pregnancy success:

  • 1-2 Days After IUI
    Symptoms may include mild cramping as the body adjusts.
  • 2-3 Days After IUI
    Symptoms of pink or light brown spotting after IUI are possible as a result of the catheter insertion.
  • 3-4 Days After IUI
    Symptoms may also include breast or nipple tenderness, fatigue, and mood swings.
  • 4-7 Days After IUI
    Watch for pink or light brown implantation bleeding, increased urination, or nausea.
  • 7-9 Days Post IUI
    Continue watching for implantation bleeding, increased urine output, and feelings of nausea.
  • 12-14 Days After IUI
    Pregnancy tests may begin to show positive results.

A Word About Spotting and Bleeding After IUI


Signs of implantation after an IUI procedure, such as light spotting or bleeding, are common and may occur anywhere from 6-12 days after the procedure as the embryo implants (connects) into the uterine wall.

Implantation bleeding is usually light pink or brown and is very minimal. If you experience heavy, bright red bleeding, contact your doctor or fertility specialist right away.

Supporting Your Family-Building Dreams With Safe, Effective IUI


Navigating the days following an IUI can be a blend of hope and anticipation—knowing what to expect can help make this journey a little easier.

If you are ready to take the next step in your fertility journey with a safe and minimally invasive IUI procedure, please schedule a consultation with Pacific Reproductive Center. We are ready to help you turn your dreams of a family into a reality.

Looking for the Best Fertility Clinic in Southern California?

Pacific Reproductive Center has four convenient locations throughout Southern California, making it easy for patients to receive quality care close to home. Each IVF fertility center has an on-site lab, next-generation services, and state-of-the-art equipment.

Whether in Glendale, Torrance, Irvine, or Corona, our world-class fertility doctors can help you build the family you’ve always wanted.


PRC Torrance
3720 Lomita Blvd, Suite 200 Torrance, CA 90505
PRC Glendale
116 E. Broadway, Suite 300 Glendale, CA 91205
PRC Irvine
10 Post Irvine, CA 92618
PRC Corona
381 Corporate Terrace Corona, CA 92879
CALL TODAY! 424-340-0871

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