In Vitro Fertilization with Donor Eggs | PRC

In Vitro Fertilization with Donor Eggs

In Vitro Fertilization with Donor Eggs

The number of donor egg IVF cycles is increasing. There were 18,000 of these procedures done in the USA in 2010. The success rate with fresh embryos from donor eggs was over 54 percent in 2011, regardless of the age of the mother (SART).

If you have struggled with getting pregnant or are a same-sex couple then an in vitro procedure with the help of donor eggs is a viable option. According to the US Centers for Disease Control and Prevention, a donor-egg IVF has the success rate of 52% of women showing positive results.

Historically, donor eggs were typically sought by females premature ovarian failure or women over 40 as their eggs have grown older and less likely to become fertilized. Now, IVF with donor eggs can be a suitable option for those who have tried IVF and failed.

The donor should be at an age younger than 35, be clear of sexually transmitted disease

Both, the recipient and the donor have to undergo certain tests to increase the probability of a successful procedure. The recipient woman using eggs from a donor should be evaluated for overall health and well-being. The recommended tests typically include screening for sexually transmitted diseases, saline sonogram/hysterosonogram to examine the uterine anatomy.


The donor would undergo a semen analysis.

In addition, the donor undergoes a full physical examination and some blood work to endure overall well-being. Clinics should present the recipient with the donor’s profile that includes his health, emotional status, family health history, education, etc. Ideally, the donor should be at an age younger than 35, be clear of sexually transmitted disease, have no indication of impaired fertility, and have genetic screening and blood tests done based on their family history.

The recipient woman will require about 2 weeks of estrogen administration, the transfer is timed based on the phase of the cycle with being progesterone administered the day of or the day before the transfer occurs.

The recipient should eat well, exercise, and avoid smoking tobacco or limit consuming alcohol in order to ensure the success of a healthy pregnancy.   Regular check-up leading up to delivery is essential.


There are no invasive procedures involved for the recipient. invasive procedures in IVF such as ovarian stimulation or egg retrieval. In order to minimize multiple pregnancies, the number of embryos being transferred should be very carefully considered between the patient and the doctor.

The reasons why donor eggs should be considered include the age of the mother’s eggs. It is difficult for women to get pregnant after age 40 as their eggs get old and become much less likely to be successfully fertilized. Using IVF with donor eggs from a younger woman is a suitable alternative in such cases, with a higher success rate. If the recipient woman has had cancer treatment (chemotherapy or radiation) or premature menopause, or the ovaries have been removed are often unable to produce eggs.

If the uterus is still intact they may be able to receive donor eggs and get pregnant. Moreover, in the setting if a genetic disease, a recipient woman might like to avoid transferring it to the offspring and choose the route getting donor eggs. This is also a popular choice in male same-sex couples who want to have a child, may find a woman to donate the egg and be the surrogate by using the sperm from one of the two males.

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