Taking Clomid for Twins | Pacific Reproductive Center

Clomid for conceiving twins – What are the chances?

Clomid for conceiving twins – What are the chances?

Clomid or Clomiphene citrate is a medication commonly used in fertility treatments. The drug stimulates the body to increase the production of egg-stimulating hormones. This causes the follicles in the ovaries to continue to mature, increasing the chance of more than one egg develop to maturity and be released during ovulation. This helps women in whom eggs do not develop and are not released on their own. Women who are anovulatory (do not ovulate without medications) often have medical conditions that alter hormone production, such as PCOS or Polycystic Ovarian Syndrome.

In some cases, Clomid increases the number of eggs released.

Can Clomid increase the chance of twins?

A woman’s ovaries contain hundreds of thousands of follicles each containing an immature egg cell. While several follicles begin the process of development every month, usually, only one of them fully develops and releases an egg. This happens because once a follicle matures, it releases hormones signaling the body to reduce the production of egg-stimulating hormones.

Clomid tricks the body into continue producing egg-stimulating hormones, causing the follicles to continue to mature and increasing the chance of more than one egg developing to maturity and be released during ovulation.

However, most twins conceived with the help of Clomid will not be identical. This is because Clomid increases the odds of your ovaries releasing more than one developed egg. Identical twins come from the same egg but in this case, the eggs would be different, hence, fraternal twins.

Remember that using a higher dosage of Clomid than necessary will not increase the odds of having twins. In fact, it may lower the chances you’ll get pregnant at all. This is because high Clomid dosage can cause the cervical mucus to be thicker and harder, making it difficult for the sperm to travel through. This is why your fertility doctor will initially prescribe the lowest dose of Clomid. S/he would increase dosage only if the lower dosage doesn’t trigger ovulation.

Are there other factors that can contribute to the likelihood of having twins?

Even without Clomid, the likelihood of becoming pregnant with more than one baby increases, based on factors like your age, height, weight, and family history.

Will I notice a difference, if I got pregnant with twins, on Clomid?

The early pregnancy symptoms are no different with twins. Only an ultrasound can confirm whether you have conceived twins. Your doctor may order an ultrasound scan at the 6-week mark (2 weeks after you miss your period), but this may not be able to detect twins. A twin pregnancy should be visible by the 8th week.

A large clinical study, involving women taking Clomid, showed that of all pregnancies –

One-baby pregnancies – 92%

Twin pregnancies – 7%

Triplet pregnancies < 1%

Quadruplet or more pregnancies – extremely rare

Clomid has an 80% success rate for ovulation and taking Clomid increases a woman’s chances of having twins by 10%.

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